| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Bridger Management Roberto Mignone | 266,916 | $65,725 | +7% | 3.56% |
| 2. | Redmile Group Jeremy Green | 355,009 | $87,417 | +4% | 2.96% |
| 3. | Sivik Global Healthcare Krishen Sud | 30,586 | $7,531 | +40% | 2.89% |
| 4. | Rock Springs Capital Management Kris Jenner, Gordon Bussard, Graham Mcphail | 223,000 | $54,912 | +67% | 2.11% |
| 5. | Columbus Circle Investors Principal Global Investors | 293,159 | $72,187 | -4% | 1.48% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $80.74 | 2,500 | Officer | 4,000 | 2015-11-23 | Filing | |
| $80.66 | 1,500 | Officer | 1,500 | 2015-11-23 | Filing | |
| $47.98 | 365 | Director | 10,325 | 2012-11-01 | Filing | |
| $47.97 | 100 | Director | 9,960 | 2012-11-01 | Filing | |
| $47.94 | 1,535 | Director | 9,860 | 2012-11-01 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $205.32 | 2,590 | Director | 14,821 | 2017-11-06 | Filing | |
| $202.24 | 539 | Director | 9,094 | 2017-11-07 | Filing | |
| $202.15 | 458 | Director | 9,633 | 2017-11-07 | Filing | |
| $174.91 | 1,600 | Officer, Director | 22,027 | 2017-09-14 | Filing | |
| $174.09 | 6,900 | Officer, Director | 23,627 | 2017-09-14 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 82,213 | $20,244 | 4.78% | |
| 2. | 14,068 | $3,464 | 3.35% | |
| 3. | 165,479 | $40,748 | 2.09% | |
| 4. | 1,652,077 | $406,808 | 1.75% | |
| 5. | 11,381 | $2,802,000 | 1.68% |
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