| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Bridger Management Roberto Mignone | 230,159 | $46,287 | 3.05% | |
| 2. | Sio Capital Michael Castor | 23,200 | $4,666 | 2.63% | |
| 3. | Sivik Global Healthcare Krishen Sud | 35,000 | $7,039 | -23% | 2.61% |
| 4. | Redmile Group Jeremy Green | 144,349 | $29,030 | 1.26% | |
| 5. | Rock Springs Capital Management Kris Jenner, Gordon Bussard, Graham Mcphail | 134,000 | $26,949 | -33% | 1.22% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $80.74 | 2,500 | Officer | 4,000 | 2015-11-23 | Filing | |
| $80.66 | 1,500 | Officer | 1,500 | 2015-11-23 | Filing | |
| $47.98 | 365 | Director | 10,325 | 2012-11-01 | Filing | |
| $47.97 | 100 | Director | 9,960 | 2012-11-01 | Filing | |
| $47.94 | 1,535 | Director | 9,860 | 2012-11-01 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $205.32 | 2,590 | Director | 14,821 | 2017-11-06 | Filing | |
| $202.24 | 539 | Director | 9,094 | 2017-11-07 | Filing | |
| $202.15 | 458 | Director | 9,633 | 2017-11-07 | Filing | |
| $174.91 | 1,600 | Officer, Director | 22,027 | 2017-09-14 | Filing | |
| $174.09 | 6,900 | Officer, Director | 23,627 | 2017-09-14 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 1,595,428 | $308,928 | 1.33% | |
| 2. | 29,372 | $5,687 | 0.54% | |
| 3. | 105,832 | $20,492 | 0.39% | |
| 4. | 4,003 | $775 | 0.18% | |
| 5. | 11,700 | $2,265 | 0.1% |
