Alnylam (ALNY): Can the RNAi Franchise Get it an Entry into the S&P 500 Index?
Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) is a biotechnology company built on RNA interference, a technique that switches off the genes behind certain diseases.
9 New Contenders for S&P 500 Index
Joining the S&P 500 is one of the clearest signs that a company has arrived.
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Okta (OKTA): Does the AI-Identity Turnaround Make It a Stronger S&P 500 Contestant?
Okta, Inc. (NASDAQ:OKTA) sells identity software, the tools that let employees and customers log in securely across a company's many apps.
Affirm Holdings (AFRM): Has BNPL's Profitability Turn Earned It an Index Seat?
Affirm Holdings, Inc. (NASDAQ:AFRM) is the largest of the "buy now, pay later" lenders. The company lets shoppers split purchases into installments at online checkouts.
First Citizens (FCNCA): Is the SVB-Boosted Bank Still Undervalued for the S&P 500 Index?
First Citizens BancShares, Inc. (NASDAQ:FCNCA) is a large regional bank whose earnings were transformed when it acquired the failed Silicon Valley Bank.
Samsara (IOT): Does a Fourth Straight Profitable Quarter Ensures its Entry into the Index?
Samsara Inc. (NYSE:IOT) sells software and sensors that help businesses track their vehicles, equipment, and workers in real time.
Ciena (CIEN): Is the AI-Optical Boom Enough to Carry It Into the S&P 500?
Ciena Corporation (NYSE:CIEN) makes the optical networking gear that carries data across the internet's backbone and between data centers, the physical plumbing behind the AI boom.
United Therapeutics (UTHR): Can the Profit-Machine Biotech Finally Crack the S&P 500?
United Therapeutics Corporation (NASDAQ:UTHR) develops treatments for pulmonary arterial hypertension, a rare and dangerous high blood pressure in the lungs, with its Tyvaso franchise at the core.
Astera Labs (ALAB): Is the AI-Connectivity Competitor Ready for the S&P 500?
Astera Labs, Inc. (NASDAQ:ALAB) makes the specialized chips and hardware that move data between processors, memory, and accelerators inside AI data centers.
CME Group (CME): Can Market Data Make Earnings Less Dependent on Trading Surges?
CME Group Inc. (NASDAQ:CME) has already shown that market data can cushion softer trading. Second-quarter 2026 market-data and information-services revenue rose 20% to $238.1 million.
T-Mobile (TMUS): Can Fiber Grow Without Consuming Too Much Shareholder Cash?
T-Mobile US, Inc. (NASDAQ:TMUS) wants fiber to deepen relationships with wireless households while partners help finance and operate the networks.
Moody’s (MCO): Can Private Credit Create a Durable Subscription Business?
Moody’s Corporation (NYSE:MCO), featured in Insider Monkey’s 10 Best Financial Stocks to Buy According to Warren Buffett, has an opportunity beyond rating debt when it is issued.
JPMorgan (JPM): Can New Branches Keep Winning Profitable Customers?
JPMorgan Chase & Co. (NYSE:JPM) is expanding branches while competitors invest in their own networks. Physical access can bring in deposits, investment accounts, and business borrowers.
Zoom (ZM): Is Cash-Rich Compounder Being Overlooked as a Potential Entrant?
Zoom Communications, Inc. (NASDAQ:ZM) is the video-meetings company that became a household name during the pandemic and is now remaking itself into an AI-first work platform.
Eaton (ETN): Will Its Electrical Backlog Translate Into Lasting Earnings Power?
Eaton Corporation plc (NYSE:ETN) is benefiting from the infrastructure needed to power data centers and modernize electricity networks.
Johnson & Johnson (JNJ): Are Its Medical Device Deals Paying Off?
Johnson & Johnson (NYSE:JNJ) is turning acquired heart technologies into growing sales.
Intuitive Surgical (ISRG): Does Leasing Make Growth More Durable or More Capital Intensive?
Intuitive Surgical, Inc. (NASDAQ:ISRG) is making robotic surgery easier for hospitals to finance. Operating leases accounted for 54% of second-quarter da Vinci placements, up from 49% a year earlier.
Tango Therapeutics (TNGX) Has Striking Pancreatic Cancer Data. How Much Is Priced In?
A Small Trial Has Created a Large Valuation Test Tango Therapeutics, Inc.
Natera (NTRA) Is Expanding Cancer Testing Rapidly. Does Its Valuation Leave Room for Error?
Testing Volume Is Growing Faster Than the Valuation Can Ignore Natera, Inc.
Merck (MRK) Has New Cancer Treatments. Can They Outgrow the Keytruda Patent Cliff?
A Growing Franchise With an Expiration Date Merck & Co., Inc. (NYSE:MRK) is trying to extend its oncology leadership before competition threatens its largest earnings engine.
Cogent Biosciences (COGT) Nears Three FDA Decisions. What Is Its Pipeline Worth?
Three Regulatory Reviews, No Established Earnings Base Cogent Biosciences, Inc.
Abbott (ABT): Can Libre Keep Growing as Glucose Monitoring Becomes More Competitive?
Abbott Laboratories (NYSE:ABT) benefits each time a patient replaces a glucose sensor.
Bristol Myers (BMY) Has New Cancer Wins. Can They Offset the Patent Cliff?
Positive Oncology Data Meets an Older-Drug Problem Bristol-Myers Squibb Company (NYSE:BMY) reported positive data from its radiopharmaceutical RYZ101 Phase III ACTION-1 trial and additional progress across...
AstraZeneca (AZN) Adds Oncology Catalysts. Is the Pipeline Worth Its Earnings Multiple?
Several Oncology Catalysts, One Earnings Question AstraZeneca PLC (NYSE:AZN) enters the October 23-27 European Society for Medical Oncology congress with multiple late-stage oncology updates, including...
Guardant Health (GH) Wins a New Breast Cancer Role. Can Its Growth Justify the Price?
A Cancer Test Approval Meets a High Valuation Guardant Health, Inc. (NASDAQ:GH) is moving beyond identifying mutations at diagnosis toward testing patients repeatedly as their cancer changes.
11 Best Cancer Stocks to Invest In Now
Cancer’s Burden Keeps the Search for Better Treatments Urgent For cancer patients, progress means more time, fewer side effects, and a better chance of recovery.
These 2 Billionaires Like Nvidia (NVDA). Should You Buy the Dip Ahead of Earnings?
Nvidia Corporation (NASDAQ:NVDA) has slipped after a rough two weeks for AI stocks. But overall, the stock remains on the radar of major investors.
What Is Twilio's (TWLO) Economic Moat, and Is It Widening or Narrowing?
Twilio Inc. (NYSE:TWLO) moves messages and calls for other companies. When a delivery service texts a tracking link or a bank sends a one-time code, something like it is underneath.
Can MongoDB (MDB) Hold Its Guidance After Losing Its Chief Executive?
MongoDB, Inc. (NASDAQ:MDB) closed at $348.69 on October 19.
Palo Alto Networks (PANW) Pays a Large Part of Its Wage Bill in Stock. What Does That Do to Profit?
Palo Alto Networks, Inc. (NASDAQ:PANW) closed at $346.95 on October 19.
Is Cloudflare (NET) Worth It When Most of Its Users Pay Nothing?
Cloudflare, Inc. (NYSE:NET) closed at $297.58 on October 19.
Can ServiceNow (NOW) Keep Growing at This Size?
ServiceNow, Inc. (NYSE:NOW) closed at $145.36 on October 19.
Host Digital Authorizes $15 Million Share Buyback Program
NEW YORK, NY, October 20th, 2026, FinanceWire Board believes the current share price does not reflect the value of Host Digital’s contracted AI data center platform Host Digital Inc.
Snowflake (SNOW) Grows Revenue 35% and Still Loses Money on Every Dollar
Snowflake Inc. (NYSE:SNOW) sells a place to keep company data and the computing power to ask questions of it. Customers pay for what they consume rather than for seats.
Is CrowdStrike (CRWD) Still Priced for Perfection After the October Selloff?
CrowdStrike Holdings, Inc. (NASDAQ:CRWD) had a hard session on October 16, falling 7% while the wider market gave up a fraction of that. The stock closed at $227.39 on October 16.
What Is Oracle's (ORCL) Economic Moat, and Is It Widening or Narrowing?
A moat is usually tested by asking what a customer would have to do to leave. For Oracle Corporation (NYSE:ORCL) that question has two answers now, and they point in opposite directions.
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