| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Perceptive Advisors Joseph Edelman | 3,970,357 | $175,489 | 4.59% | |
| 2. | Cadian Capital Eric Bannasch | 2,051,934 | $90,695 | -5% | 4.36% |
| 3. | Broadfin Capital Kevin Kotler | 622,380 | $27,509 | +16% | 4.33% |
| 4. | RA Capital Management Peter Kolchinsky | 1,145,268 | $50,621 | 3.28% | |
| 5. | Scopia Capital Matt Sirovich And Jeremy Mindich | 3,507,728 | $155,042 | +2% | 2.7% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $52.00 | 100,000 | Large Shareholder | 4,070,357 | 2018-08-10 | Filing | |
| $36.59 | 1,346 | Officer | 4,033 | 2017-12-13 | Filing | |
| $37.50 | 300,000 | Large Shareholder | 3,970,357 | 2017-10-03 | Filing | |
| $27.67 | 22,055 | Large Shareholder | 3,670,357 | 2017-09-29 | Filing | |
| $40.14 | 8,920 | Large Shareholder | 3,648,302 | 2017-09-29 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $53.16 | 1,900 | Officer | 7,143 | 2018-08-08 | Filing | |
| $52.42 | 5,100 | Officer | 9,043 | 2018-08-08 | Filing | |
| $45.00 | 5,118 | Officer | 7,143 | 2018-06-12 | Filing | |
| $39.90 | 218 | Director | 0 | 2018-05-16 | Filing | |
| $44.83 | 24,716 | Director | 0 | 2018-03-12 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 362,010 | $16,001 | 4.78% | |
| 2. | 150,845 | $6,667 | 3.18% | |
| 3. | 69,746 | $3,083 | 2.04% | |
| 4. | 80,160 | $3,543 | 1.19% | |
| 5. | 478,000 | $21,128 | 0.87% |
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