| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Perceptive Advisors Joseph Edelman | 3,970,357 | $175,489 | 4.59% | |
| 2. | Cadian Capital Eric Bannasch | 2,051,934 | $90,695 | -5% | 4.36% |
| 3. | Broadfin Capital Kevin Kotler | 622,380 | $27,509 | +16% | 4.33% |
| 4. | RA Capital Management Peter Kolchinsky | 1,145,268 | $50,621 | 3.28% | |
| 5. | Eversept Partners Kamran Moghtaderi | 150,845 | $6,667 | -27% | 3.18% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $52.00 | 100,000 | Large Shareholder | 4,070,357 | 2018-08-10 | Filing | |
| $36.59 | 1,346 | Officer | 4,033 | 2017-12-13 | Filing | |
| $37.50 | 300,000 | Large Shareholder | 3,970,357 | 2017-10-03 | Filing | |
| $27.67 | 22,055 | Large Shareholder | 3,670,357 | 2017-09-29 | Filing | |
| $40.14 | 8,920 | Large Shareholder | 3,648,302 | 2017-09-29 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $43.74 | 1,961 | Officer | 7,143 | 2018-10-04 | Filing | |
| $43.11 | 2,900 | Officer | 9,104 | 2018-10-04 | Filing | |
| $42.92 | 2,100 | Officer | 12,004 | 2018-10-04 | Filing | |
| $48.21 | 2,300 | Officer | 7,143 | 2018-09-04 | Filing | |
| $47.27 | 4,700 | Officer | 9,443 | 2018-09-04 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 60,000 | $2,976 | 0.29% | |
| 2. | 7,381 | $366 | 0.15% | |
| 3. | 1,384 | $68 | 0% | |
| 4. | 167 | $8 | 0% |
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