| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Perceptive Advisors Joseph Edelman | 4,907,139 | $132,542 | +43% | 2.14% |
| 2. | RA Capital Management Peter Kolchinsky | 3,677,424 | $99,327 | -31% | 1.93% |
| 3. | VenBio Select Advisor Kurt Von Emster | 2,250,000 | $60,773 | -20% | 1.2% |
| 4. | Farallon Capital Thomas Steyer | 2,000,000 | $54,020 | -12% | 0.44% |
| 5. | D E Shaw D. E. Shaw | 1,555,155 | $42,005 | +59% | 0.05% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $25.45 | 1,000 | Officer | 5,913 | 2020-05-08 | Filing | |
| $20.48 | 2,500 | Director | 2,500 | 2020-03-23 | Filing | |
| $19.69 | 1,000 | Officer | 10,015 | 2020-03-18 | Filing | |
| $21.83 | 8,000 | Director | 8,000 | 2020-03-13 | Filing | |
| $52.00 | 100,000 | Large Shareholder | 4,070,357 | 2018-08-10 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $28.21 | 2,573 | Officer | 5,048 | 2020-05-12 | Filing | |
| $18.51 | 6,158 | Officer, Director | 55,590 | 2020-03-19 | Filing | |
| $52.20 | 5,270 | Officer, Director | 56,708 | 2020-01-08 | Filing | |
| $51.83 | 28,955 | Officer, Director | 61,978 | 2020-01-08 | Filing | |
| $52.09 | 7,550 | Officer | 1,387 | 2020-01-02 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 60,734 | $1,640,426 | 0% | |
| 2. | 4,725,506 | $127,636 | 0% | |
| 3. | 4,360 | $117,756 | 0.03% | |
| 4. | 4,112,288 | $111,074 | 0% | |
| 5. | 2,786 | $75,250 | 0% |
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