| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Biotechnology Value Fund / BVF Inc Mark Lampert | 3,586,658 | $151,787 | +13% | 6.07% |
| 2. | Redmile Group Jeremy Green | 2,615,030 | $110,668 | +2% | 3.45% |
| 3. | Baker Bros. Advisors Julian Baker And Felix Baker | 2,384,742 | $100,922 | 0.57% | |
| 4. | VenBio Select Advisor Kurt Von Emster | 816,500 | $34,554 | +49% | 0.63% |
| 5. | Rock Springs Capital Management Kris Jenner, Gordon Bussard, Graham Mcphail | 755,875 | $31,989 | +2% | 0.8% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $14.78 | 3,223 | Director, Other | 230,637 | 2022-05-27 | Filing | |
| $14.21 | 10,642 | Director, Other | 227,414 | 2022-05-26 | Filing | |
| $14.78 | 26,353 | Director, Other | 1,627,928 | 2022-05-27 | Filing | |
| $14.21 | 90,372 | Director, Other | 1,601,575 | 2022-05-26 | Filing | |
| $14.78 | 35,793 | Director, Other | 2,195,696 | 2022-05-27 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $53.27 | 1,422 | Officer | 17,514 | 2022-01-12 | Filing | |
| $52.13 | 7,151 | Officer | 18,936 | 2022-01-12 | Filing | |
| $51.21 | 6,427 | Officer | 26,087 | 2022-01-12 | Filing | |
| $53.97 | 241 | Officer, Director | 472,199 | 2022-01-12 | Filing | |
| $53.27 | 1,623 | Officer, Director | 472,440 | 2022-01-12 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 430,243 | $18,207,883 | 0% | |
| 2. | 6,875,698 | $290,980 | 36.78% | |
| 3. | 3,895,205 | $164,845 | 0.01% | |
| 4. | 3,419,084 | $144,698 | 0% | |
| 5. | 3,225,749 | $136,514 | 0.02% |
