| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Sectoral Asset Management Jerome Pfund And Michael Sjostrom | 956,036 | $28,251 | +14% | 3.37% |
| 2. | Deerfield Management James E. Flynn | 3,032,987 | $89,625 | +89% | 3.21% |
| 3. | Consonance Capital Management Mitchell Blutt | 1,506,695 | $44,523 | -12% | 3.15% |
| 4. | DAFNA Capital Management Nathan Fischel | 205,440 | $6,071 | +36% | 2.28% |
| 5. | Highland Capital Management James Dondero | 778,791 | $23,013 | +49% | 1.34% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $23.73 | 100,000 | Large Shareholder | 2,050,477 | 2019-08-14 | Filing | |
| $25.52 | 178,903 | Large Shareholder | 1,310,000 | 2019-08-13 | Filing | |
| $24.92 | 71,097 | Large Shareholder | 1,131,097 | 2019-08-13 | Filing | |
| $24.43 | 189,555 | Large Shareholder | 1,060,000 | 2019-08-12 | Filing | |
| $41.75 | 2,000 | Director | 19,800 | 2018-11-16 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $47.02 | 1,500 | Officer | 95,743 | 2019-02-01 | Filing | |
| $46.03 | 9,500 | Officer | 97,243 | 2019-02-01 | Filing | |
| $35.21 | 11,000 | Officer | 106,743 | 2019-01-02 | Filing | |
| $40.55 | 299 | Officer | 117,743 | 2018-12-03 | Filing | |
| $39.79 | 10,701 | Officer | 118,042 | 2018-12-03 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 1,672,714 | $49,429 | 27.78% | |
| 2. | 1,950,477 | $57,637 | 18.9% | |
| 3. | 600,000 | $17,730 | 5.01% | |
| 4. | 120,230 | $3,552 | 3.85% | |
| 5. | 570,036 | $16,845 | 2.36% |
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