Xenon Pharmaceuticals Inc. (XENE)

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Institutional Investors' Holdings

Filing Period:

No.	Name	Shares	Value	% Port
1.	Fmr Llc	10,818,491	$629,095,252	0.03%
2.	Blackrock, Inc.	5,640,118	$327,972,862	0.01%
3.	Wellington Management Group Llp	4,829,641	$280,843,625	0.05%
4.	Henderson Group Plc	4,175,982	$242,858,453	0.12%
5.	Capital International Investors	2,674,727	$155,535,375	0.04%