Xenon Pharmaceuticals Inc. (XENE)

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Institutional Investors' Holdings

Filing Period:

No.	Name	Shares	Value	% Port
1.	Fmr Llc	5,655,922	$260,511,767	0.02%
2.	Wellington Management Group Llp	4,162,654	$191,731,844	0.03%
3.	Capital World Investors	2,681,537	$123,511,594	0.02%
4.	Capital International Investors	2,455,683	$113,108,759	0.02%
5.	Paradigm Biocapital Advisors Lp	2,127,400	$97,988,044	4.58%