| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | VenBio Select Advisor Kurt Von Emster | 5,777,777 | $335,977,733 | +7% | 3.31% |
| 2. | Driehaus Capital Richard Driehaus | 4,491,653 | $261,189,622 | -2% | 1.92% |
| 3. | Polar Capital Brian Ashford-Russell And Tim Woolley | 4,405,312 | $256,168,893 | +79% | 0.91% |
| 4. | Citadel Investment Group Ken Griffin | 2,652,990 | $154,271,368 | +101% | 0.02% |
| 5. | Deerfield Management James E. Flynn | 1,615,696 | $93,952,722 | +199% | 1.11% |