| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | VenBio Select Advisor Kurt Von Emster | 4,985,000 | $152,391 | 2.78% | |
| 2. | Driehaus Capital Richard Driehaus | 3,300,427 | $100,894 | +6% | 1.23% |
| 3. | Perceptive Advisors Joseph Edelman | 2,411,447 | $73,718 | 1.47% | |
| 4. | Polar Capital Brian Ashford-Russell And Tim Woolley | 2,190,059 | $66,950 | +30% | 0.3% |
| 5. | Point72 Asset Management Steve Cohen | 2,146,450 | $65,617 | -29% | 0.26% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $28.81 | 700 | Officer | 700 | 2022-01-21 | Filing | |
| $24.40 | 4,000 | Officer | 4,000 | 2021-12-06 | Filing | |
| $2.22 | 15,000 | Director | 44,210 | 2017-11-15 | Filing | |
| $2.95 | 8,000 | Director | 29,210 | 2017-09-22 | Filing | |
| $2.95 | 2,000 | Director | 21,210 | 2017-09-21 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $30.80 | 2,500 | Director | 193,135 | 2022-03-08 | Filing | |
| $30.50 | 2,500 | Director | 183,135 | 2022-03-08 | Filing | |
| $30.55 | 2,500 | Director | 185,635 | 2022-03-08 | Filing | |
| $30.20 | 2,500 | Director | 188,135 | 2022-03-08 | Filing | |
| $30.10 | 2,500 | Director | 190,635 | 2022-03-08 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 42,502 | $1,299,000 | 0.02% | |
| 2. | 28,836 | $881,518 | 0% | |
| 3. | 3,833,476 | $117,190 | 0% | |
| 4. | 2,274,974 | $69,546 | 0.01% | |
| 5. | 1,790,743 | $54,743 | 0.14% |
