| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Aquilo Capital Management Marc Schneidman | 1,166,736 | $15,296 | +23% | 5.74% |
| 2. | Parkman Healthcare Partners Greg Martinez | 588,059 | $7,709 | 2.22% | |
| 3. | Biotechnology Value Fund / BVF Inc Mark Lampert | 1,949,075 | $25,552 | +12% | 1.93% |
| 4. | DAFNA Capital Management Nathan Fischel | 248,854 | $3,262 | -25% | 1.11% |
| 5. | Dorset Management David M. Knott | 195,657 | $2,565 | +5% | 1.03% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $2.22 | 15,000 | Director | 44,210 | 2017-11-15 | Filing | |
| $2.95 | 8,000 | Director | 29,210 | 2017-09-22 | Filing | |
| $2.95 | 2,000 | Director | 21,210 | 2017-09-21 | Filing | |
| $2.90 | 6,312 | Director | 19,210 | 2017-08-18 | Filing | |
| $2.65 | 23 | Director | 12,898 | 2017-08-17 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $9.51 | 10,395 | Officer, Director | 258,122 | 2019-09-20 | Filing | |
| $9.39 | 5,206 | Director | 118,955 | 2019-09-20 | Filing | |
| $9.27 | 7,600 | Director | 124,161 | 2019-09-19 | Filing | |
| $9.28 | 4,368 | Director | 131,761 | 2019-09-18 | Filing | |
| $9.32 | 5,069 | Director | 136,129 | 2019-09-17 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 917,500 | $12,028 | 2.97% | |
| 2. | 161,600 | $2,118 | 2.04% | |
| 3. | 992,107 | $13,007 | 0.61% | |
| 4. | 243,470 | $3,192 | 0.51% | |
| 5. | 1,274,100 | $16,703 | 0.47% |
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