| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | VenBio Select Advisor Kurt Von Emster | 4,798,101 | $236,546 | +10% | 9.1% |
| 2. | Broadfin Capital Kevin Kotler | 1,020,178 | $50,295 | -30% | 7.91% |
| 3. | Ghost Tree Capital Ken Greenberg And David Kim | 500,000 | $24,650 | +91% | 7.25% |
| 4. | Cormorant Asset Management Bihua Chen | 1,918,350 | $94,575 | 6.99% | |
| 5. | Biotechnology Value Fund / BVF Inc Mark Lampert | 745,000 | $36,729 | 3.58% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $38.85 | 400,000 | Large Shareholder | 4,798,101 | 2018-06-11 | Filing | |
| $38.85 | 193,050 | Large Shareholder | 1,565,560 | 2018-06-07 | Filing | |
| $13.00 | 255,264 | Large Shareholder | 3,135,966 | 2017-11-16 | Filing | |
| $13.00 | 144,736 | Large Shareholder | 1,372,510 | 2017-11-16 | Filing | |
| $13.00 | 650,000 | Large Shareholder | 4,360,601 | 2017-11-16 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $58.40 | 1,862 | 50,932 | 2018-08-23 | Filing | ||
| $57.86 | 32,514 | 52,794 | 2018-08-23 | Filing | ||
| $56.88 | 17,434 | 85,308 | 2018-08-23 | Filing | ||
| $51.33 | 29 | 3,394 | 2018-06-27 | Filing | ||
| $50.15 | 736 | 3,423 | 2018-06-27 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 3,135,966 | $154,603 | 25.09% | |
| 2. | 1,565,560 | $77,182 | 8.73% | |
| 3. | 99,656 | $4,913 | 0.77% | |
| 4. | 16,429 | $810 | 0.71% | |
| 5. | 29,099 | $1,435 | 0.7% |
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