| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Broadfin Capital Kevin Kotler | 1,443,948 | $44,329 | -42% | 6.9% |
| 2. | VenBio Select Advisor Kurt Von Emster | 4,398,101 | $135,022 | 6.44% | |
| 3. | Cormorant Asset Management Bihua Chen | 1,918,350 | $58,893 | +56% | 4.39% |
| 4. | Ghost Tree Capital Ken Greenberg And David Kim | 262,500 | $8,059 | -57% | 1.63% |
| 5. | Iguana Healthcare Management Stuart Weisbrod | 55,000 | $1,689 | 1.11% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $38.85 | 400,000 | Large Shareholder | 4,798,101 | 2018-06-11 | Filing | |
| $38.85 | 193,050 | Large Shareholder | 1,565,560 | 2018-06-07 | Filing | |
| $13.00 | 255,264 | Large Shareholder | 3,135,966 | 2017-11-16 | Filing | |
| $13.00 | 144,736 | Large Shareholder | 1,372,510 | 2017-11-16 | Filing | |
| $13.00 | 650,000 | Large Shareholder | 4,360,601 | 2017-11-16 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $51.33 | 29 | 3,394 | 2018-06-27 | Filing | ||
| $50.15 | 736 | 3,423 | 2018-06-27 | Filing | ||
| $49.43 | 4,234 | 4,159 | 2018-06-27 | Filing | ||
| $49.27 | 1,150 | 3,394 | 2018-06-26 | Filing | ||
| $48.62 | 4,058 | 4,027 | 2018-06-26 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 8,000 | $394 | 0% | |
| 2. | 0 | $0 | 0% | |
| 3. | 129 | $6 | 0% |
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