| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Redmile Group Jeremy Green | 361,676 | $40,982 | +2% | 1.25% |
| 2. | Park West Asset Management Peter S. Park | 175,297 | $19,863 | -37% | 0.72% |
| 3. | GAMCO Investors Mario Gabelli | 34,000 | $3,853 | -3% | 0.02% |
| 4. | Driehaus Capital Richard Driehaus | 4,700 | $533 | 0.01% | |
| 5. | Winton Capital Management David Harding | 5,562 | $630 | -13% | 0.01% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $90.00 | 1,000 | Director | 3,294 | 2017-05-04 | Filing | |
| $66.87 | 1,750 | Director | 1,750 | 2016-11-25 | Filing | |
| $32.49 | 1,000 | Director | 5,500 | 2016-03-08 | Filing | |
| $29.05 | 500 | Director | 4,500 | 2015-05-18 | Filing | |
| $14.00 | 7,143 | Director | 7,143 | 2014-11-30 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $105.00 | 2 | Officer, Director | 6,430 | 2018-11-30 | Filing | |
| $104.00 | 1,629 | Officer, Director | 105,000 | 2018-11-30 | Filing | |
| $104.41 | 1,210 | Officer | 31,902 | 2018-12-03 | Filing | |
| $104.00 | 1,790 | Officer | 33,112 | 2018-11-30 | Filing | |
| $102.00 | 4,000 | Director | 25,074 | 2018-11-29 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 57,485 | $6,514 | 1.38% | |
| 2. | 71,728 | $8,127 | 1.3% | |
| 3. | 99,300 | $11,252 | 1.17% | |
| 4. | 86,401 | $9,790 | 0.64% | |
| 5. | 29,196 | $3,308 | 0.54% |
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