| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Redmile Group Jeremy Green | 196,396 | $15,753 | 0.68% | |
| 2. | Daruma Asset Management Mariko Gordon | 15,624 | $1,253 | +10% | 0.07% |
| 3. | Marshall Wace LLP Paul Marshall And Ian Wace | 120,664 | $9,678 | +46% | 0.05% |
| 4. | Royce & Associates Chuck Royce | 36,000 | $2,888 | +72% | 0.01% |
| 5. | GAMCO Investors Mario Gabelli | 35,000 | $2,807 | 0.01% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $90.00 | 1,000 | Director | 3,294 | 2017-05-04 | Filing | |
| $66.87 | 1,750 | Director | 1,750 | 2016-11-25 | Filing | |
| $32.49 | 1,000 | Director | 5,500 | 2016-03-08 | Filing | |
| $29.05 | 500 | Director | 4,500 | 2015-05-18 | Filing | |
| $14.00 | 7,143 | Director | 7,143 | 2014-11-30 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $86.02 | 6,500 | Officer | 92,446 | 2017-11-30 | Filing | |
| $87.02 | 7,025 | Officer | 98,946 | 2017-11-29 | Filing | |
| $88.19 | 800 | Officer | 105,971 | 2017-11-28 | Filing | |
| $88.54 | 1 | Officer | 106,771 | 2017-11-27 | Filing | |
| $102.21 | 825 | Officer | 38,114 | 2017-08-31 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 62,953 | $4,978 | 0.9% | |
| 2. | 0 | $0 | 0% | |
| 3. | 2,680 | $212 | 0% | |
| 4. | 1,504 | $119 | 0% | |
| 5. | 0 | $0 | 0% |
