| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Redmile Group Jeremy Green | 354,776 | $36,822 | +49% | 1.25% |
| 2. | Park West Asset Management Peter S. Park | 275,297 | $28,573 | +1% | 1.06% |
| 3. | GAMCO Investors Mario Gabelli | 35,000 | $3,633 | 0.02% | |
| 4. | Winton Capital Management David Harding | 6,369 | $661 | -50% | 0.01% |
| 5. | Marshall Wace LLP Paul Marshall And Ian Wace | 32,662 | $3,390 | -71% | 0.01% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $90.00 | 1,000 | Director | 3,294 | 2017-05-04 | Filing | |
| $66.87 | 1,750 | Director | 1,750 | 2016-11-25 | Filing | |
| $32.49 | 1,000 | Director | 5,500 | 2016-03-08 | Filing | |
| $29.05 | 500 | Director | 4,500 | 2015-05-18 | Filing | |
| $14.00 | 7,143 | Director | 7,143 | 2014-11-30 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $114.00 | 1,250 | Officer | 24,374 | 2018-10-01 | Filing | |
| $113.00 | 1,250 | Officer | 25,624 | 2018-09-28 | Filing | |
| $112.00 | 1,250 | Officer | 26,874 | 2018-09-13 | Filing | |
| $111.00 | 1,250 | Officer | 28,124 | 2018-09-13 | Filing | |
| $104.00 | 633 | Officer | 8,573 | 2018-08-31 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 71,728 | $8,127 | 1.3% | |
| 2. | 5,600 | $635 | 0.16% | |
| 3. | 5,000 | $567 | 0.09% | |
| 4. | 3,000 | $340 | 0.01% | |
| 5. | 2,310 | $262 | 0.01% |
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