| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | RA Capital Management Peter Kolchinsky | 5,062,759 | $14,125 | -56% | 1.18% |
| 2. | VenBio Select Advisor Kurt Von Emster | 4,006,893 | $11,179 | -17% | 0.72% |
| 3. | 683 Capital Partners Ari Zweiman | 2,500,000 | $6,975 | -1% | 0.58% |
| 4. | Perceptive Advisors Joseph Edelman | 2,958,116 | $8,253 | -14% | 0.27% |
| 5. | Polar Capital Brian Ashford-Russell And Tim Woolley | 8,077,429 | $22,536 | +96% | 0.23% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $2.46 | 203,200 | Large Shareholder | 17,283,670 | 2018-04-10 | Filing | |
| $2.43 | 32,100 | Large Shareholder | 17,080,470 | 2018-04-09 | Filing | |
| $2.24 | 685,676 | Large Shareholder | 17,048,370 | 2018-04-06 | Filing | |
| $2.46 | 203,200 | Large Shareholder | 17,283,670 | 2018-04-10 | Filing | |
| $2.43 | 32,100 | Large Shareholder | 17,080,470 | 2018-04-09 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $0.82 | 3,075 | Officer | 14,506 | 2015-01-16 | Filing | |
| $0.80 | 4,484 | Officer | 76,131 | 2015-01-07 | Filing | |
| $0.80 | 4,484 | Officer | 16,437 | 2015-01-07 | Filing | |
| $0.80 | 519 | Officer | 17,581 | 2015-01-07 | Filing | |
| $0.80 | 4,484 | Officer, Director | 17,035 | 2015-01-07 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 500 | $1 | 0% | |
| 2. | 10,665 | $31 | 0% | |
| 3. | 10,000 | $29 | 0% |
