| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Renaissance Technologies Jim Simons | 2,048,000 | $297,288 | -12% | 0.28% |
| 2. | Palo Alto Investors William Leland Edwards | 502,745 | $72,978 | -11% | 6.11% |
| 3. | Deerfield Management James E. Flynn | 376,000 | $54,580 | 1.73% | |
| 4. | Great Point Partners Jeffrey Jay And David Kroin | 216,144 | $31,375 | 3.27% | |
| 5. | Adage Capital Management Phill Gross And Robert Atchinson | 170,912 | $24,810 | 0.07% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $60.17 | 7,500 | Director | 157,869 | 2015-05-29 | Filing | |
| $19.86 | 100,000 | Director | 282,398 | 2013-05-07 | Filing | |
| $15.20 | 56,017 | Director | 172,398 | 2013-02-25 | Filing | |
| $14.70 | 43,983 | Director | 116,381 | 2013-02-22 | Filing | |
| $6.86 | 15,000 | Director | 65,000 | 2009-02-27 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $250.00 | 7,500 | Director | 15,152 | 2020-06-05 | Filing | |
| $182.14 | 626 | Director | 188,939 | 2020-05-04 | Filing | |
| $181.46 | 6,584 | Director | 189,565 | 2020-05-04 | Filing | |
| $180.39 | 1,100 | Director | 196,149 | 2020-05-04 | Filing | |
| $179.35 | 1,400 | Director | 197,249 | 2020-05-04 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 3 | $0 | 0% |
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