Xenon Pharmaceuticals Inc. (XENE)

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Institutional Investors' Holdings

Filing Period: Filing is Ongoing

No.	Name	Shares	Value	% Port
1.	Fmr Llc	8,287,499	$278,045,591	0.02%
2.	Wellington Management Group Llp	3,789,197	$127,127,560	0.02%
3.	Capital International Investors	3,088,730	$103,626,892	0.02%
4.	Capital World Investors	2,224,715	$74,639,188	0.01%
5.	Blackrock, Inc.	2,036,125	$68,311,992	0%