| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | VenBio Select Advisor Kurt Von Emster | 5,777,777 | $348,746,620 | 3.13% | |
| 2. | Polar Capital Brian Ashford-Russell And Tim Woolley | 4,570,556 | $275,878,760 | +4% | 0.65% |
| 3. | Driehaus Capital Richard Driehaus | 4,418,557 | $266,704,101 | -2% | 1.55% |
| 4. | Deerfield Management James E. Flynn | 1,615,696 | $97,523,411 | 1.02% | |
| 5. | Citadel Investment Group Ken Griffin | 1,401,242 | $84,578,967 | -48% | 0.01% |