| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | VenBio Select Advisor Kurt Von Emster | 5,777,777 | $348,746,620 | 3.13% | |
| 2. | Polar Capital Brian Ashford-Russell And Tim Woolley | 4,570,556 | $275,878,760 | +4% | 0.65% |
| 3. | Driehaus Capital Richard Driehaus | 4,418,557 | $266,704,101 | -2% | 1.55% |
| 4. | Deerfield Management James E. Flynn | 1,615,696 | $97,523,411 | 1.02% | |
| 5. | Citadel Investment Group Ken Griffin | 1,401,242 | $84,578,967 | -48% | 0.01% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $28.81 | 700 | $20,167.00 | 700 | 2022-01-21 | Filing | |
| $24.40 | 4,000 | $97,600.00 | 4,000 | 2021-12-06 | Filing | |
| $2.22 | 15,000 | $33,280.50 | 44,210 | 2017-11-15 | Filing | |
| $2.95 | 8,000 | $23,600.00 | 29,210 | 2017-09-22 | Filing | |
| $2.95 | 2,000 | $5,900.00 | 21,210 | 2017-09-21 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $60.98 | 700 | $42,683.62 | 2 | 2026-08-28 | Filing | |
| $60.17 | 6,368 | $383,145.37 | 702 | 2026-08-28 | Filing | |
| $64.06 | 10,000 | $640,550.00 | 1,870 | 2026-08-11 | Filing | |
| $53.14 | 1,322 | $70,251.08 | 24,896 | 2026-06-05 | Filing | |
| $53.14 | 1,190 | $63,236.60 | 1,455 | 2026-06-05 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 9,647,998 | $582,353,159 | 0.03% | |
| 2. | 7,522,482 | $454,057,014 | 0.01% | |
| 3. | 4,186,519 | $252,673,122 | 0.1% | |
| 4. | 2,617,360 | $157,381,859 | 0.01% | |
| 5. | 2,361,639 | $142,548,530 | 0.03% |
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