| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Deerfield Management James E. Flynn | 2,573,305 | $56,664 | +710% | 1.98% |
| 2. | Broadfin Capital Kevin Kotler | 570,598 | $12,565 | 1.97% | |
| 3. | Eversept Partners Kamran Moghtaderi | 61,300 | $1,350 | 0.64% | |
| 4. | OrbiMed Advisors Samuel Isaly | 1,689,000 | $37,192 | 0.44% | |
| 5. | Granite Point Capital Warren Lammert | 225,000 | $4,955 | 0.44% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $28.50 | 1,754 | Director | 1,754 | 2018-08-03 | Filing | |
| $3.84 | 8,103 | Director | 22,001 | 2018-03-06 | Filing | |
| $3.88 | 6,300 | Director | 6,300 | 2018-03-06 | Filing | |
| $3.89 | 6,300 | Director | 6,300 | 2018-03-06 | Filing | |
| $3.96 | 2,418 | Director | 2,500 | 2018-03-06 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $6.52 | 15,000 | Officer | 7,763 | 2016-08-01 | Filing | |
| $10.61 | 2,000 | Officer | 5,295 | 2016-05-02 | Filing | |
| $10.00 | 2,000 | Officer | 5,295 | 2016-04-22 | Filing | |
| $10.01 | 4,000 | Officer | 5,295 | 2016-03-07 | Filing | |
| $11.47 | 2,000 | Officer | 5,295 | 2016-01-04 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 76,000 | $3,256 | 0.25% | |
| 2. | 4,730 | $203 | 0.08% | |
| 3. | 10,000 | $428 | 0% | |
| 4. | 75 | $3 | 0% | |
| 5. | 370 | $16 | 0% |
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