| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | RA Capital Management Peter Kolchinsky | 6,995,858 | $168,110,468 | 1.78% | |
| 2. | Driehaus Capital Richard Driehaus | 4,395,572 | $105,625,595 | -9% | 0.78% |
| 3. | Samsara BioCapital Srini Akkaraju And Michael Dybbs | 3,149,128 | $75,673,546 | 7.35% | |
| 4. | Siren L.L.C. Raymond Debbane | 2,000,000 | $48,060,000 | 1.33% | |
| 5. | Biotechnology Value Fund / BVF Inc Mark Lampert | 1,353,249 | $32,518,573 | -22% | 1.04% |