Septerna Inc. (SEPN)

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Sector: Healthcare

Hedge Fund Popularity

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Hedge Fund Holdings

Filing Period:

Last updated on March 25, 2026, 5:07pm based on SEC 13F filings Last update: March 25, 2026, 5:07pm

No.	Hedge Fund	Shares	Value	Activity	% Port
1.	RA Capital Management Peter Kolchinsky	6,995,858	$195,044,521		2%
2.	Driehaus Capital Richard Driehaus	4,809,470	$134,088,024	-3%	0.91%
3.	Samsara BioCapital Srini Akkaraju And Michael Dybbs	3,149,128	$87,797,689		9.06%
4.	Siren L.L.C. Raymond Debbane	2,000,000	$55,760,000	-10%	1.66%
5.	Biotechnology Value Fund / BVF Inc Mark Lampert	1,720,782	$47,975,402	-58%	1.61%

Insider Trading: Purchases See All

Insider	Price	Amount	Total Value	Remaining Holdings	Date	Form 4
Ezekowitz	$6.93	13,319	$92,270.04	117,420	2025-03-07	Filing
Ezekowitz	$6.00	41,355	$248,130.00	104,101	2025-03-06	Filing
Ezekowitz	$5.82	37,835	$220,260.24	62,746	2025-03-05	Filing
Ezekowitz	$6.35	7,491	$47,543.88	24,911	2025-03-04	Filing
Finer	$5.80	3,000	$17,400.00	771,907	2025-02-27	Filing

Insider Trading: Sales See All

Insider	Price	Amount	Total Value	Remaining Holdings	Date	Form 4
Bhatt	$25.86	326	$8,431.11	174,209	2026-04-15	Filing
Bhatt	$25.24	1,101	$27,788.58	174,535	2026-04-15	Filing
Bhatt	$23.76	2,573	$61,123.67	175,636	2026-04-15	Filing
Shaikhly	$28.14	66,363	$1,867,342.00	793	2026-03-02	Filing
Shaikhly	$27.51	4,090	$112,496.27	67,156	2026-03-02	Filing

Institutional Investors' Holdings

Filing Period: Filing is Ongoing

No.	Name	Shares	Value	% Port
1.	Trv Gp V, Llc	6,215,591	$149,360,652	37.25%
2.	Trv Gp Vi, Llc	4,211,659	$101,206,166	74.64%
3.	Vanguard Capital Management Llc	1,196,962	$28,762,997	0%
4.	Vanguard Portfolio Management Llc	195,043	$4,686,883	0%
5.	Vanguard Fiduciary Trust Co	154,484	$3,712,251	0%