| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | RA Capital Management Peter Kolchinsky | 5,210,088 | $116,185 | -4% | 2.26% |
| 2. | Baker Bros. Advisors Julian Baker And Felix Baker | 2,700,055 | $60,211 | -1% | 0.26% |
| 3. | Deerfield Management James E. Flynn | 2,470,013 | $55,081 | -19% | 1.6% |
| 4. | Rock Springs Capital Management Kris Jenner, Gordon Bussard, Graham Mcphail | 512,111 | $11,420 | +3% | 0.31% |
| 5. | Marshall Wace LLP Paul Marshall And Ian Wace | 301,568 | $6,725 | 0.04% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $26.42 | 378,501 | Director | 3,074,893 | 2018-06-25 | Filing | |
| $17.00 | 100,000 | Large Shareholder | 2,696,392 | 2017-10-10 | Filing | |
| $17.00 | 100,000 | Large Shareholder, Director | 2,696,392 | 2017-10-10 | Filing | |
| $17.00 | 550,000 | Large Shareholder | 4,909,956 | 2017-10-10 | Filing | |
| $17.00 | 550,000 | Large Shareholder | 4,909,956 | 2017-10-10 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $30.00 | 25,000 | Officer | 43,602 | 2020-08-31 | Filing | |
| $22.04 | 44,153 | Large Shareholder | 5,140,408 | 2020-07-02 | Filing | |
| $21.87 | 25,527 | Large Shareholder | 5,184,561 | 2020-07-01 | Filing | |
| $22.15 | 61,901 | Large Shareholder | 5,210,088 | 2020-06-30 | Filing | |
| $25.04 | 300 | Director | 1,909,258 | 2020-06-26 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 19,063 | $425,104 | 0% | |
| 2. | 5,960 | $132,899 | 0.03% | |
| 3. | 4,912,306 | $109,544 | 4.4% | |
| 4. | 4,410,488 | $98,353 | 0.05% | |
| 5. | 2,795,841 | $62,347 | 0% |
