| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Baker Bros. Advisors Julian Baker And Felix Baker | 6,498,267 | $115,929,083 | +3% | 0.63% |
| 2. | RA Capital Management Peter Kolchinsky | 5,516,067 | $98,406,635 | 2.22% | |
| 3. | Alkeon Capital Management Panayotis Takis Sparaggis | 2,015,966 | $35,964,833 | -10% | 0.07% |
| 4. | Polar Capital Brian Ashford-Russell And Tim Woolley | 1,750,000 | $31,220,000 | +40% | 0.22% |
| 5. | Rock Springs Capital Management Kris Jenner, Gordon Bussard, Graham Mcphail | 1,597,123 | $28,492,674 | -10% | 0.67% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $20.17 | 10,000 | Officer, Director | 111,335 | 2021-03-30 | Filing | |
| $26.42 | 378,501 | Director | 3,074,893 | 2018-06-25 | Filing | |
| $17.00 | 100,000 | Large Shareholder | 2,696,392 | 2017-10-10 | Filing | |
| $17.00 | 100,000 | Large Shareholder, Director | 2,696,392 | 2017-10-10 | Filing | |
| $17.00 | 550,000 | Large Shareholder | 4,909,956 | 2017-10-10 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $17.50 | 912 | Officer | 7,872 | 2023-03-29 | Filing | |
| $27.03 | 1,177 | Officer | 3,827 | 2023-02-14 | Filing | |
| $26.87 | 554 | Officer | 3,741 | 2023-02-14 | Filing | |
| $26.87 | 635 | Officer | 4,940 | 2023-02-14 | Filing | |
| $26.87 | 702 | Officer | 59,406 | 2023-02-14 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 7,607,311 | $135,714,428 | 0.11% | |
| 2. | 5,310,703 | $94,742,942 | 0.02% | |
| 3. | 3,891,683 | $69,427,625 | 0.17% | |
| 4. | 3,780,599 | $67,442,767 | 0% | |
| 5. | 2,909,956 | $51,913,615 | 3.58% |
