| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Sarissa Capital Management Alex Denner | 1,417,000 | $18,010 | 2.24% | |
| 2. | Palo Alto Investors William Leland Edwards | 1,405,680 | $17,866 | +20% | 0.86% |
| 3. | Partner Fund Management Christopher Medlock James | 2,838,376 | $36,076 | +10% | 0.68% |
| 4. | Tang Capital Management Kevin C. Tang | 349,400 | $4,441 | 0.6% | |
| 5. | Rock Springs Capital Management Kris Jenner, Gordon Bussard, Graham Mcphail | 534,400 | $6,792 | +17% | 0.24% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $82.49 | 28 | Officer | 30 | 2014-04-11 | Filing | |
| $87.35 | 2 | Officer | 2 | 2014-04-09 | Filing | |
| $38.92 | 22,549 | Large Shareholder | 5,686,668 | 2013-11-08 | Filing | |
| $39.60 | 280,700 | Large Shareholder | 5,664,119 | 2013-11-05 | Filing | |
| $40.08 | 54,200 | Large Shareholder | 5,383,419 | 2013-10-09 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $9.01 | 1 | Large Shareholder, Officer, Director | 4,189,008 | 2019-08-02 | Filing | |
| $9.03 | 516 | Large Shareholder, Officer, Director | 4,189,009 | 2019-08-02 | Filing | |
| $9.00 | 94 | Officer | 36,812 | 2019-08-02 | Filing | |
| $10.04 | 1,852 | Officer | 19,557 | 2019-07-22 | Filing | |
| $10.10 | 1,841 | Officer | 36,906 | 2019-07-22 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 127,029 | $1,615 | 0.59% | |
| 2. | 29,100 | $370 | 0.49% | |
| 3. | 454,300 | $5,774 | 0.4% | |
| 4. | 27,567 | $350 | 0.37% | |
| 5. | 262,945 | $3,342 | 0.26% |
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