| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Farallon Capital Thomas Steyer | 2,750,000 | $53,763 | +10% | 0.38% |
| 2. | Adage Capital Management Phill Gross And Robert Atchinson | 2,520,600 | $49,278 | +15% | 0.12% |
| 3. | Biotechnology Value Fund / BVF Inc Mark Lampert | 2,372,288 | $46,378 | +1% | 2.52% |
| 4. | Consonance Capital Management Mitchell Blutt | 2,369,709 | $46,328 | 5.64% | |
| 5. | Baker Bros. Advisors Julian Baker And Felix Baker | 1,596,198 | $31,206 | -17% | 0.12% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $6.70 | 12,000 | Director | 15,310 | 2020-03-12 | Filing | |
| $5.70 | 8,000 | Director | 8,000 | 2019-12-03 | Filing | |
| $5.13 | 30,000 | Officer | 49,500 | 2019-12-03 | Filing | |
| $5.09 | 562 | Officer | 1,175 | 2019-12-03 | Filing | |
| $5.10 | 613 | Officer | 613 | 2019-12-03 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $17.19 | 2,499 | Director | 0 | 2020-08-11 | Filing | |
| $8.85 | 3,395 | Officer | 49,802 | 2019-08-06 | Filing | |
| $8.85 | 10,792 | Officer, Director | 374,792 | 2019-08-06 | Filing | |
| $8.03 | 810 | Officer | 51,197 | 2019-03-01 | Filing | |
| $8.03 | 2,183 | Officer, Director | 383,831 | 2019-03-01 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 7,106 | $138,922 | 0% | |
| 2. | 3,408,961 | $66,645 | 1.6% | |
| 3. | 2,455,977 | $48,013 | 0% | |
| 4. | 2,449,183 | $47,882 | 9.63% | |
| 5. | 1,552,459 | $30,352 | 0% |
