| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | OrbiMed Advisors Samuel Isaly | 4,081,592 | $36,612 | 0.59% | |
| 2. | Biotechnology Value Fund / BVF Inc Mark Lampert | 1,589,495 | $14,258 | 0.57% | |
| 3. | Avidity Partners Management David Witzke And Michael Gregory | 1,207,000 | $10,827 | -11% | 0.22% |
| 4. | Renaissance Technologies Jim Simons | 386,094 | $3,463 | -1% | 0% |
| 5. | Tiger Management Julian Robertson | 137,728 | $1,235 | 0.2% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $7.10 | 112,665 | Large Shareholder | 1,484,115 | 2022-02-11 | Filing | |
| $10.17 | 1,900 | Director | 1,900 | 2021-09-23 | Filing | |
| $10.08 | 15,000 | Director | 50,000 | 2021-09-23 | Filing | |
| $9.80 | 10,000 | Director | 35,000 | 2021-09-21 | Filing | |
| $9.40 | 425,531 | Large Shareholder, Director | 425,531 | 2021-09-17 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $13.92 | 17,013 | Officer | 7,014 | 2021-12-31 | Filing | |
| $10.08 | 15,000 | Director | 50,000 | 2021-09-23 | Filing | |
| $10.17 | 1,900 | Director | 1,900 | 2021-09-23 | Filing | |
| $9.40 | 400,000 | Large Shareholder | 2,600,980 | 2021-09-17 | Filing | |
| $10.01 | 45,262 | Large Shareholder, Officer, Director | 109,387 | 2021-09-17 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 4,708,288 | $42,233 | 12.94% | |
| 2. | 4,185,757 | $37,546 | 3.19% | |
| 3. | 3,777 | $33,880 | 0% | |
| 4. | 2,029,580 | $18,205 | 3.72% | |
| 5. | 1,484,693 | $13,318 | 12.36% |
