Alpine Immune Sciences Inc. (ALPN)

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Institutional Investors' Holdings

Filing Period:

No.	Name	Shares	Value	% Port
1.	Paradigm Biocapital Advisors Lp	3,176,743	$60,548,722	2.83%
2.	Frazier Life Sciences Management, L.p.	3,131,008	$59,677,012	3.19%
3.	Blackrock Inc.	3,058,498	$58,294,972	0%
4.	Vanguard Group Inc	2,234,767	$42,594,660	0%
5.	State Street Corp	1,390,029	$26,493,953	0%