| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | VenBio Select Advisor Kurt Von Emster | 3,542,500 | $333,526,375 | +13% | 4.31% |
| 2. | Commodore Capital Egen Atkinson And Michael Kramarz | 3,525,000 | $331,878,750 | 16.2% | |
| 3. | Deerfield Management James E. Flynn | 3,046,916 | $286,867,141 | -10% | 4.38% |
| 4. | HBK Investments David Costen Haley | 2,850,000 | $268,327,500 | 2.94% | |
| 5. | Woodline Partners Michael Rockefeller And Karl Kroeker | 1,674,167 | $157,622,823 | +9% | 0.74% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $14.38 | 14,706 | $211,431.10 | 40,576 | 2022-11-03 | Filing | |
| $22.92 | 5,826 | $133,558.14 | 25,870 | 2022-08-22 | Filing | |
| $22.99 | 704 | $16,186.93 | 20,044 | 2022-08-19 | Filing | |
| $22.97 | 4,340 | $99,684.59 | 19,340 | 2022-07-12 | Filing | |
| $19.75 | 26,894 | $531,156.50 | 462,015 | 2021-03-30 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $95.92 | 8,300 | $796,136.00 | 11,002 | 2025-11-25 | Filing | |
| $60.00 | 25,000 | $1,500,000.00 | 0 | 2025-07-17 | Filing | |
| $55.00 | 16,805 | $924,275.00 | 0 | 2025-07-10 | Filing | |
| $55.00 | 6,695 | $368,225.00 | 0 | 2025-07-09 | Filing | |
| $52.76 | 34,000 | $1,793,840.00 | 0 | 2025-06-20 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 4,373,770 | $411,790,446 | 11.71% | |
| 2. | 2,810,935 | $264,649,564 | 0.01% | |
| 3. | 2,172,015 | $204,495,213 | 0% | |
| 4. | 2,132,489 | $200,773,839 | 0.84% | |
| 5. | 2,025,277 | $190,679,830 | 2.35% |