| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Commodore Capital Egen Atkinson And Michael Kramarz | 3,525,000 | $185,415,000 | -22% | 13.09% |
| 2. | Deerfield Management James E. Flynn | 3,384,628 | $178,031,433 | +7% | 3.23% |
| 3. | VenBio Select Advisor Kurt Von Emster | 3,155,555 | $165,982,193 | +6% | 2.91% |
| 4. | Holocene Advisors Brandon Haley | 2,225,241 | $117,047,677 | +19% | 0.29% |
| 5. | Polar Capital Brian Ashford-Russell And Tim Woolley | 1,611,049 | $84,741,177 | -6% | 0.44% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $14.38 | 14,706 | $211,431.10 | 40,576 | 2022-11-03 | Filing | |
| $22.92 | 5,826 | $133,558.14 | 25,870 | 2022-08-22 | Filing | |
| $22.99 | 704 | $16,186.93 | 20,044 | 2022-08-19 | Filing | |
| $22.97 | 4,340 | $99,684.59 | 19,340 | 2022-07-12 | Filing | |
| $19.75 | 26,894 | $531,156.50 | 462,015 | 2021-03-30 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $60.00 | 25,000 | $1,500,000.00 | 0 | 2025-07-17 | Filing | |
| $55.00 | 16,805 | $924,275.00 | 0 | 2025-07-10 | Filing | |
| $55.00 | 6,695 | $368,225.00 | 0 | 2025-07-09 | Filing | |
| $52.76 | 34,000 | $1,793,840.00 | 0 | 2025-06-20 | Filing | |
| $48.55 | 1,000 | $48,550.00 | 11,002 | 2025-03-21 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 7,490,377 | $393,993,838 | 0.02% | |
| 2. | 4,281,954 | $225,230,780 | 9.62% | |
| 3. | 4,000,553 | $210,429,088 | 3% | |
| 4. | 3,726,723 | $196,025,630 | 0.04% | |
| 5. | 2,042,388 | $107,429,609 | 0.45% |
