| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Perceptive Advisors Joseph Edelman | 6,948,277 | $91,578 | 1.33% | |
| 2. | OrbiMed Advisors Samuel Isaly | 4,102,925 | $54,077 | 0.59% | |
| 3. | Adage Capital Management Phill Gross And Robert Atchinson | 2,125,000 | $28,008 | -4% | 0.05% |
| 4. | 683 Capital Partners Ari Zweiman | 1,315,100 | $17,333 | +2% | 0.67% |
| 5. | Royce & Associates Chuck Royce | 683,800 | $9,012 | -6% | 0.06% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $12.85 | 500,000 | Large Shareholder, Director | 6,933,277 | 2020-11-23 | Filing | |
| $16.31 | 5,000 | Director | 5,000 | 2019-11-19 | Filing | |
| $23.50 | 425,531 | Large Shareholder, Director | 6,433,277 | 2019-08-12 | Filing | |
| $13.80 | 1,304,348 | Large Shareholder | 6,007,746 | 2019-03-01 | Filing | |
| $15.00 | 1,333,333 | Large Shareholder, Director | 4,703,398 | 2018-06-12 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $19.86 | 15,000 | Officer, Director | 1,080,781 | 2021-11-17 | Filing | |
| $20.53 | 3,200 | Officer, Director | 1,095,781 | 2021-11-16 | Filing | |
| $19.82 | 11,800 | Officer, Director | 1,098,981 | 2021-11-16 | Filing | |
| $21.28 | 6,956 | Officer | 819,218 | 2021-10-20 | Filing | |
| $20.93 | 13,744 | Officer | 826,174 | 2021-10-20 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 324,019 | $4,270,571 | 0% | |
| 2. | 7,447 | $98,151 | 0% | |
| 3. | 2,898,550 | $38,203 | 3.35% | |
| 4. | 2,003,020 | $26,400 | 0% | |
| 5. | 1,896,464 | $24,996 | 0% |
