| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | VenBio Select Advisor Kurt Von Emster | 2,565,555 | $318,282,753 | 4.39% | |
| 2. | Redmile Group Jeremy Green | 1,733,189 | $215,019,427 | -14% | 7.69% |
| 3. | Woodline Partners Michael Rockefeller And Karl Kroeker | 481,979 | $59,794,315 | +50% | 0.65% |
| 4. | 412,000 | $51,112,720 | +48658% | 4.78% | |
| 5. | Balyasny Asset Management Dmitry Balyasny | 256,604 | $31,834,292 | +687% | 0.05% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $20.00 | 25,000 | Large Shareholder, Officer, Director | 2,001,462 | 2018-10-18 | Filing | |
| $20.00 | 25,000 | Large Shareholder, Officer, Director | 2,036,462 | 2018-10-18 | Filing | |
| $12.45 | 1,018 | Large Shareholder, Officer, Director | 1,976,462 | 2018-06-06 | Filing | |
| $11.15 | 13,116 | Large Shareholder, Officer, Director | 1,975,444 | 2018-06-06 | Filing | |
| $10.75 | 10,866 | Large Shareholder, Officer, Director | 1,962,328 | 2018-06-05 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $174.00 | 1,314 | Large Shareholder, Officer, Director | 1,612,262 | 2024-03-11 | Filing | |
| $173.09 | 3,359 | Large Shareholder, Officer, Director | 1,613,576 | 2024-03-11 | Filing | |
| $172.06 | 2,816 | Large Shareholder, Officer, Director | 1,616,935 | 2024-03-11 | Filing | |
| $170.93 | 8,002 | Large Shareholder, Officer, Director | 1,619,751 | 2024-03-11 | Filing | |
| $170.32 | 5,109 | Large Shareholder, Officer, Director | 1,627,753 | 2024-03-11 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 2,435,774 | $302,182,123 | 0% | |
| 2. | 2,385,898 | $295,994,506 | 0.02% | |
| 3. | 1,809,547 | $224,492,402 | 0% | |
| 4. | 1,237,497 | $153,523,878 | 0% | |
| 5. | 988,460 | $122,628,348 | 6.55% |
