| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Miura Global Management Pasco Alfaro / Richard Tumure | 60,000 | $28,709 | 6.77% | |
| 2. | Healthcor Management LP Arthur B Cohen And Joseph Healey | 176,010 | $84,217 | -38% | 2.67% |
| 3. | Rock Springs Capital Management Kris Jenner, Gordon Bussard, Graham Mcphail | 141,900 | $67,896 | -2% | 2.61% |
| 4. | Sivik Global Healthcare Krishen Sud | 12,500 | $5,981 | 2.29% | |
| 5. | Atika Capital Brad Farber | 18,000 | $8,612 | +10% | 1.65% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $250.19 | 1,000 | Director | 2,000 | 2010-11-19 | Filing | |
| $281.05 | 1,000 | Director | 1,000 | 2010-09-13 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $521.19 | 245 | Director | 317,789 | 2018-08-06 | Filing | |
| $520.24 | 35,672 | Officer, Director | 327,870 | 2018-08-06 | Filing | |
| $508.50 | 8,250 | Officer | 9,821 | 2018-07-30 | Filing | |
| $522.00 | 2,500 | Director, Other | 0 | 2018-07-24 | Filing | |
| $523.46 | 262 | Officer, Other | 1,970 | 2018-07-24 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | Cpmg IncPUT | 1,547,000 | $740,209 | 66.37% |
| 2. | 74,711 | $35,748 | 9.01% | |
| 3. | 35,158 | $16,822 | 8.82% | |
| 4. | 24,073 | $11,518 | 8.36% | |
| 5. | 19,066 | $9,120 | 6.92% |
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