| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Healthcor Management LP Arthur B Cohen And Joseph Healey | 235,205 | $126,994 | 4.8% | |
| 2. | Rock Springs Capital Management Kris Jenner, Gordon Bussard, Graham Mcphail | 152,500 | $82,339 | 3.28% | |
| 3. | Unio Capital John Allison | 9,176 | $4,954 | +6% | 3.17% |
| 4. | Coatue Management Philippe Laffont | 533,254 | $287,920 | -8% | 2.46% |
| 5. | OrbiMed Advisors Samuel Isaly | 205,600 | $111,010 | -3% | 2.1% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $250.19 | 1,000 | Director | 2,000 | 2010-11-19 | Filing | |
| $281.05 | 1,000 | Director | 1,000 | 2010-09-13 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $584.63 | 35 | Officer | 159 | 2019-12-06 | Filing | |
| $584.63 | 36 | Officer | 159 | 2019-12-06 | Filing | |
| $584.63 | 59 | Officer | 159 | 2019-12-06 | Filing | |
| $584.63 | 59 | Officer | 159 | 2019-12-06 | Filing | |
| $584.63 | 36 | Officer | 159 | 2019-12-06 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 21,925 | $12,961 | 6.29% | |
| 2. | 45,715 | $27,024 | 5.76% | |
| 3. | 39,375 | $23,277 | 3.79% | |
| 4. | 20,171 | $11,924 | 3.65% | |
| 5. | 10,352 | $6,120 | 3.41% |
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