| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | VenBio Select Advisor Kurt Von Emster | 9,000,000 | $658,350 | +18% | 11.33% |
| 2. | Paulson & Co John Paulson | 7,991,440 | $584,574 | +20% | 15.17% |
| 3. | Renaissance Technologies Jim Simons | 6,798,963 | $497,344 | -23% | 0.54% |
| 4. | Viking Global Andreas Halvorsen | 3,662,876 | $267,939 | +213% | 0.73% |
| 5. | Perceptive Advisors Joseph Edelman | 3,084,042 | $225,597 | 2.42% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $9.48 | 10,000 | Director | 25,448 | 2017-05-10 | Filing | |
| $31.32 | 10,000 | Director | 10,000 | 2015-08-19 | Filing | |
| $9.76 | 6,000 | Director | 6,000 | 2014-08-14 | Filing | |
| $6.50 | 32,075 | Director | 178,406 | 2013-12-13 | Filing | |
| $6.50 | 32,075 | Director | 178,478 | 2013-12-13 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $90.30 | 6,165 | Officer | 105,665 | 2021-04-12 | Filing | |
| $89.60 | 8,195 | Officer | 111,830 | 2021-04-12 | Filing | |
| $88.70 | 51,253 | Officer | 120,025 | 2021-04-12 | Filing | |
| $90.28 | 15,000 | Director | 0 | 2021-04-12 | Filing | |
| $93.51 | 70,739 | Officer | 52,675 | 2021-04-01 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 694,025 | $63,878,061 | 0.1% | |
| 2. | 15,377,169 | $1,415,314 | 0.04% | |
| 3. | 1,894,201 | $174,370 | 0.39% | |
| 4. | 1,758,012 | $161,807 | 1.46% | |
| 5. | 1,417,476 | $130,465 | 0.13% |
