| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Endurant Capital Management Vishal Saluja And Pham Quang | 387,698 | $10,592 | +14% | 3.95% |
| 2. | Sirios Capital Management John Brennan | 2,920,903 | $79,799 | +12% | 3.93% |
| 3. | JANA Partners Barry Rosenstein | 4,724,275 | $129,067 | 3.84% | |
| 4. | Sio Capital Michael Castor | 225,463 | $6,160 | +51% | 3.7% |
| 5. | OrbiMed Advisors Samuel Isaly | 10,377,795 | $283,521 | -1% | 3.51% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $27.50 | 13 | Director | 32,337 | 2017-09-01 | Filing | |
| $27.80 | 30 | Director | 32,324 | 2017-06-16 | Filing | |
| $25.52 | 29 | Director | 32,294 | 2017-04-24 | Filing | |
| $16.49 | 30,000 | Director | 41,598 | 2016-02-12 | Filing | |
| $16.53 | 100,000 | Other | 500,000 | 2015-08-21 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $34.00 | 33,512 | Officer | 89,162 | 2018-07-10 | Filing | |
| $32.42 | 5,000 | Officer | 24,201 | 2018-07-02 | Filing | |
| $32.64 | 19,323 | Officer | 89,162 | 2018-06-14 | Filing | |
| $35.87 | 36,730 | Officer | 71,151 | 2018-06-11 | Filing | |
| $32.00 | 31,056 | Officer | 107,881 | 2018-06-11 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 1,247,052 | $40,779 | 1.34% | |
| 2. | 89,902 | $2,940 | 1.05% | |
| 3. | 16,337 | $534 | 0.91% | |
| 4. | 111,905 | $3,659 | 0.86% | |
| 5. | 28,635 | $936 | 0.58% |
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