| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Sarissa Capital Management Alex Denner | 643,000 | $149,703 | 18.76% | |
| 2. | 550,000 | $128,051 | 4.84% | ||
| 3. | Camber Capital Management Stephen Dubois | 350,000 | $81,487 | 4.28% | |
| 4. | Factorial Partners Mark Kleiman | 14,650 | $3,410,813 | +11% | 3.27% |
| 5. | Healthcor Management LP Arthur B Cohen And Joseph Healey | 356,860 | $83,084 | 3.14% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $231.24 | 38,000 | Director | 643,000 | 2019-05-02 | Filing | |
| $229.46 | 30,000 | Director | 605,000 | 2019-05-01 | Filing | |
| $229.25 | 50,342 | Director | 575,000 | 2019-04-30 | Filing | |
| $231.48 | 4,351 | Officer, Director | 21,007 | 2019-05-01 | Filing | |
| $328.45 | 7,000 | Director | 524,658 | 2019-02-01 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $292.35 | 1,055 | Director | 6,995 | 2019-12-02 | Filing | |
| $328.55 | 6,114 | Director | 18,587 | 2019-03-18 | Filing | |
| $350.00 | 1,000 | Officer | 4,281 | 2018-09-26 | Filing | |
| $290.83 | 259 | Officer | 6,553 | 2018-02-27 | Filing | |
| $293.44 | 908 | Officer | 6,553 | 2018-02-23 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 176,710 | $41,142 | 15.79% | |
| 2. | 242,145 | $56,376 | 3.64% | |
| 3. | 303,400 | $70,668 | 3.57% | |
| 4. | 14,260,012 | $3,320,016 | 2.65% | |
| 5. | 257,939 | $60,053 | 2.62% |
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