| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Sarissa Capital Management Alex Denner | 643,000 | $190,797 | 15.83% | |
| 2. | Camber Capital Management Stephen Dubois | 350,000 | $103,856 | 5.28% | |
| 3. | Redmile Group Jeremy Green | 457,500 | $135,754 | 3.24% | |
| 4. | Partner Fund Management Christopher Medlock James | 228,328 | $67,752 | 3.22% | |
| 5. | GMT Capital Thomas E. Claugus | 277,370 | $82,304 | +8% | 3.17% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $231.24 | 38,000 | Director | 643,000 | 2019-05-02 | Filing | |
| $229.46 | 30,000 | Director | 605,000 | 2019-05-01 | Filing | |
| $229.25 | 50,342 | Director | 575,000 | 2019-04-30 | Filing | |
| $231.48 | 4,351 | Officer, Director | 21,007 | 2019-05-01 | Filing | |
| $328.45 | 7,000 | Director | 524,658 | 2019-02-01 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $292.35 | 1,055 | Director | 6,995 | 2019-12-02 | Filing | |
| $328.55 | 6,114 | Director | 18,587 | 2019-03-18 | Filing | |
| $350.00 | 1,000 | Officer | 4,281 | 2018-09-26 | Filing | |
| $290.83 | 259 | Officer | 6,553 | 2018-02-27 | Filing | |
| $293.44 | 908 | Officer | 6,553 | 2018-02-23 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 102,219 | $30,331 | 4.85% | |
| 2. | 243,419 | $72,230 | 4.33% | |
| 3. | 1,839 | $546 | 3.92% | |
| 4. | 18,114 | $5,375 | 3.8% | |
| 5. | 20,808 | $6,174 | 3.38% |
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