| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Consonance Capital Management Mitchell Blutt | 3,175,535 | $47,093 | +70% | 3.5% |
| 2. | EcoR1 Capital Oleg Nodelman | 2,590,680 | $38,420 | +9% | 4.01% |
| 3. | Baker Bros. Advisors Julian Baker And Felix Baker | 1,541,618 | $22,862 | 0.14% | |
| 4. | Rock Springs Capital Management Kris Jenner, Gordon Bussard, Graham Mcphail | 1,500,000 | $22,245 | 0.91% | |
| 5. | Citadel Investment Group Ken Griffin | 1,123,450 | $16,661 | +12% | 0% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $41.77 | 1,200 | Officer, Director | 669,291 | 2018-07-19 | Filing | |
| $41.19 | 1,200 | Officer, Director | 668,091 | 2018-07-19 | Filing | |
| $5.56 | 1,555 | Officer, Director | 634,391 | 2016-02-11 | Filing | |
| $5.52 | 8,445 | Officer, Director | 632,836 | 2016-02-10 | Filing | |
| $0.92 | 13,000 | Officer, Director | 58,000 | 2014-05-27 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $14.22 | 1,254 | Officer | 38,661 | 2020-03-30 | Filing | |
| $15.04 | 7,812 | Officer | 137,009 | 2020-03-31 | Filing | |
| $21.00 | 1,460 | Officer | 22,915 | 2019-12-13 | Filing | |
| $25.00 | 33,061 | Officer | 127,821 | 2019-12-12 | Filing | |
| $40.01 | 336 | Officer | 613,611 | 2018-09-06 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 11,237 | $166,645 | 0% | |
| 2. | 8,620 | $127,835 | 0% | |
| 3. | 2,340,828 | $34,714 | 0.04% | |
| 4. | 2,297,866 | $34,079 | 0% | |
| 5. | 1,486,400 | $22,043 | 0% |
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