| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Biotechnology Value Fund / BVF Inc Mark Lampert | 19,822,436 | $40,239,545 | 1.44% | |
| 2. | Renaissance Technologies Jim Simons | 828,321 | $1,681,492 | +4% | 0% |
| 3. | Millennium Management Israel Englander | 291,532 | $591,810 | +38% | 0% |
| 4. | Citadel Investment Group Ken Griffin | 145,999 | $296,378 | -4% | 0% |
| 5. | Marshall Wace LLP Paul Marshall And Ian Wace | 135,841 | $275,757 | -36% | 0% |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 1,024,608 | $2,079,954 | 0% | |
| 2. | 411,307 | $834,954 | 0% | |
| 3. | 381,354 | $774,148 | 0% | |
| 4. | 253,375 | $514,351 | 0% | |
| 5. | 198,686 | $403,135 | 0% |
