8. Illinois
Deaths 1,835
Drug Overdose Death Rate 14.4
Illinois went from having 825 deaths in 1999 to 1,835 in 2015. Unlike Massachusetts and North Carolina, Illinois has a bigger problem with heroin rather than fentanyl. While there are states that have ups and downs with this problem, Illinois is one of the states with a steady rise regarding the epidemic drug deaths from year to year.

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