2. Ohio
Deaths 3,310
Drug Overdose Death Rate 29.3
Ohio had 467 drug overdose deaths back in 1999, which is not that bad, but only when compared to recent numbers from just two years ago. The difference is leaving us speechless. Even though multiple drugs are blamed for taking this many lives, fentanyl seems to find its way on the top of the list, leaving heroin in the second place.

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