| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1.) | Dafna Capital Management Nathan Fischel |
251,654 | $2,839 | +200% |
4.59% |
| 2.) | Deerfield Management James E. Flynn |
4,898,227 | $55,252 |  |
3.3% |
| 3.) | Sectoral Asset Management J�R�Me Pfund And Michael Sj�Str�M |
3,529,655 | $39,815 | |
1.22% |
| 4.) | Clough Capital Partners Charles Clough |
732,700 | $8,265 | |
0.3% |
| 5.) | Perella Weinberg Partners Daniel Arbess |
444,034 | $5,008 |  |
0.29% |
| 6.) | Orbimed Advisors Samuel Isaly |
2,730,143 | $3,080 | |
0.07% |
| 7.) | Ellington Mike Vranos |
27,300 | $308 | |
0.06% |
| 8.) | Palo Alto Investors William Leland Edwards |
44,129 | $498 | |
0.05% |
| 9.) | Visium Asset Management Jacob Gottlieb |
189,650 | $2,139 | |
0.05% |
| 10.) | Millennium Management Israel Englander |
713,104 | $8,044 | |
0.03% |
| 11.) | Stevens Capital Management Matthew Tewksbury |
18,352 | $207 | |
0% |
| 12.) | Broadfin Capital Kevin Kotler |
0 | $0 |  |
0% |
| 13.) | Iridian Asset Management David Cohen And Harold Levy |
20,940 | $236 | |
0% |
| 14.) | Realm Partners Robert Millard |
0 | $0 | |
0% |
| 15.) | Ardsley Partners Philip Hempleman |
0 | $0 | |
0% |
| 16.) | Hbk Investments David Costen Haley |
15,800 | $178 | |
0% |
| 17.) | Adage Capital Management Phill Gross And Robert Atchinson |
191,100 | $2,156 | |
0% |
| 18.) | 4,900 | $55 | |
0% | |
| 19.) | 2,700 | $30 | +100% |
0% | |
| 20.) | Citadel Investment Group Ken Griffin |
147,022 | $1,658 | |
0% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $13.73 | 5,000 | Officer | 15,071 | 2013-06-10 | Filing | |
| $13.73 | 5,000 | Officer | 20,071 | 2013-06-10 | Filing | |
| $13.65 | 427 | Officer | 6,476 | 2013-06-10 | Filing | |
| $12.67 | 15,724 | Officer | 20,071 | 2013-05-13 | Filing | |
| $10.98 | 427 | Officer | 6,903 | 2013-03-11 | Filing |
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