Stock Market Movers: 10 Biggest Gainers and Losers – 19 October 2026

Page 6 of 6

2. IRON: Disc Medicine (IRON) extends winning streak to 3rd day, soars 38.86% amid strong results from phase 3 trial of drug candidate Bitopertin in treating patients with Erythropoietic Protoporphyria (EPP).

1. SLN: Silence Therapeutics (SLN) soars 125.58% on Merck’s $1.3B acquisition offer, with each share to be acquired at a 130% premium over its closing price on Friday.

Page 6 of 6