| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Biotechnology Value Fund / BVF Inc Mark Lampert | 2,250,000 | $6,908 | 0.83% | |
| 2. | Highbridge Capital Management Glenn Russell Dubin | 192,500 | $591 | +93% | 0.01% |
| 3. | Marshall Wace LLP Paul Marshall And Ian Wace | 272,657 | $837 | -56% | 0% |
| 4. | Millennium Management Israel Englander | 357,615 | $1,098 | +93% | 0% |
| 5. | Ellington Mike Vranos | 0 | $0 | 0% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $3.95 | 60,538 | Director | 130,000 | 2017-12-05 | Filing | |
| $2.45 | 30,000 | Director | 69,462 | 2017-05-15 | Filing | |
| $6.95 | 1,000 | Officer | 2,000 | 2015-06-29 | Filing | |
| $7.12 | 500 | Officer | 2,500 | 2015-06-29 | Filing | |
| $7.11 | 2,000 | Officer, Director | 226,924 | 2015-06-29 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $6.46 | 2,070 | Director | 0 | 2015-08-24 | Filing | |
| $10.96 | 930 | Director | 2,070 | 2015-03-19 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 188,447 | $562 | 0.18% | |
| 2. | 18,825 | $56 | 0% | |
| 3. | 1,000 | $2 | 0% | |
| 4. | 17,453 | $52 | 0% | |
| 5. | 45,000 | $134 | 0% |
