| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Biotechnology Value Fund / BVF Inc Mark Lampert | 3,513,994 | $11,807 | +77% | 1.54% |
| 2. | 11,250,000 | $9,047 | 0.63% | ||
| 3. | 21,625,000 | $17,240 | 0.5% | ||
| 4. | 3,500,000 | $2,760 | 0.12% | ||
| 5. | 2,000,000 | $1,560 | 0.09% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $7.31 | 5,000 | Director | 135,000 | 2018-09-28 | Filing | |
| $7.30 | 3,000 | Officer | 10,700 | 2018-09-28 | Filing | |
| $7.00 | 3,000 | Officer | 23,286 | 2018-09-28 | Filing | |
| $7.00 | 2,000 | Officer, Director | 221,234 | 2018-09-28 | Filing | |
| $7.49 | 4,000 | Director | 4,000 | 2018-09-28 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $6.46 | 2,070 | Director | 0 | 2015-08-24 | Filing | |
| $10.96 | 930 | Director | 2,070 | 2015-03-19 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 1,190,358 | $3,999 | 11.14% | |
| 2. | 2,000,000 | $1,560 | 0.99% | |
| 3. | 7,500,000 | $6,038 | 0.39% | |
| 4. | 2,500,000 | $1,974 | 0.36% | |
| 5. | 173,441 | $583 | 0.32% |
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