| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Consonance Capital Management Mitchell Blutt | 3,072,275 | $51,768 | 4.73% | |
| 2. | Armistice Capital Steven Boyd | 2,600,000 | $43,810 | -3% | 3.35% |
| 3. | Palo Alto Investors William Leland Edwards | 4,155,670 | $70,023 | 2.99% | |
| 4. | VenBio Select Advisor Kurt Von Emster | 2,775,191 | $46,762 | +97% | 2.23% |
| 5. | Hawk Ridge Management David Brown | 258,877 | $4,362 | 1.27% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $8.97 | 3,239 | Large Shareholder, Other | 1,103,617 | 2015-12-16 | Filing | |
| $8.97 | 4,441 | Large Shareholder, Other | 2,740,122 | 2015-12-16 | Filing | |
| $8.97 | 3,490 | Large Shareholder, Other | 2,152,952 | 2015-12-16 | Filing | |
| $8.61 | 93,634 | Large Shareholder, Other | 1,100,378 | 2015-12-11 | Filing | |
| $8.61 | 128,374 | Large Shareholder, Other | 2,735,681 | 2015-12-11 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $18.72 | 60,966 | Officer, Director | 1,182,872 | 2018-03-01 | Filing | |
| $18.72 | 8,532 | Officer | 199,534 | 2018-03-01 | Filing | |
| $18.71 | 3,660 | Officer | 115,073 | 2018-03-01 | Filing | |
| $18.72 | 8,525 | Officer | 139,841 | 2018-03-01 | Filing | |
| $15.30 | 21,535 | Officer, Director | 1,183,838 | 2018-01-02 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 984,584 | $16,590 | 8.88% | |
| 2. | 250,000 | $4,213 | 1.16% | |
| 3. | 64,040 | $1,079 | 0.93% | |
| 4. | 170,834 | $2,879 | 0.53% | |
| 5. | 184,900 | $3,116 | 0.43% |
