| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Select Equity Group Robert Joseph Caruso | 1,683,329 | $429,215,228 | -6% | 3.51% |
| 2. | Miura Global Management Pasco Alfaro / Richard Tumure | 55,000 | $14,024 | +10% | 2.79% |
| 3. | Redmile Group Jeremy Green | 176,586 | $45,026 | +3% | 1.73% |
| 4. | Osterweis Capital Management John Osterweis | 88,201 | $22,489 | -3% | 1.59% |
| 5. | Rock Springs Capital Management Kris Jenner, Gordon Bussard, Graham Mcphail | 92,500 | $23,586 | +1% | 1% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $203.82 | 1,000 | Director | 1,760 | 2017-06-21 | Filing | |
| $62.89 | 100 | Director | 9,212 | 2012-08-17 | Filing | |
| $52.37 | 1,100 | Director | 2,000 | 2011-08-24 | Filing | |
| $52.36 | 200 | Director | 900 | 2011-08-24 | Filing | |
| $52.35 | 100 | Director | 700 | 2011-08-24 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $283.90 | 1,981 | Director | 68,556 | 2018-06-11 | Filing | |
| $282.70 | 2,716 | Director | 70,537 | 2018-06-11 | Filing | |
| $281.72 | 2,921 | Director | 73,253 | 2018-06-11 | Filing | |
| $281.00 | 1,713 | Director | 76,174 | 2018-06-11 | Filing | |
| $284.57 | 1,347 | Officer | 1,419 | 2018-06-12 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 4,949 | $1,262 | 8.29% | |
| 2. | 187,593 | $47,832 | 3.01% | |
| 3. | 2,263,065 | $577,037 | 2.98% | |
| 4. | 20,120 | $5,130 | 2.69% | |
| 5. | 10,000 | $2,550 | 2.65% |
