| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Citadel Investment Group Ken Griffin | 2,111,518 | $46,960 | +276% | 0.01% |
| 2. | Adage Capital Management Phill Gross And Robert Atchinson | 1,830,439 | $40,709 | +8% | 0.08% |
| 3. | Nantahala Capital Management Wilmot B. Harkey And Daniel Mack | 1,798,453 | $39,998 | +35% | 1.23% |
| 4. | Frazier Healthcare Partners Alan Frazier | 1,405,045 | $31,248 | +7% | 2.4% |
| 5. | Ghost Tree Capital Ken Greenberg And David Kim | 1,350,000 | $30,024 | +218% | 6.69% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $8.00 | 12,500 | 43,900 | 2020-02-04 | Filing | ||
| $5.40 | 11,000 | 31,400 | 2019-10-10 | Filing | ||
| $7.29 | 7,200 | 20,400 | 2019-05-13 | Filing | ||
| $7.56 | 13,200 | 13,200 | 2019-05-09 | Filing | ||
| $4.87 | 8 | 7,230 | 2019-03-21 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $20.55 | 35,156 | 48,336 | 2021-02-08 | Filing | ||
| $20.19 | 15,000 | 17,659 | 2021-02-01 | Filing | ||
| $22.97 | 15,000 | 17,659 | 2020-12-01 | Filing | ||
| $22.89 | 16,334 | 0 | 2020-11-23 | Filing | ||
| $23.58 | 7,954 | 16,334 | 2020-11-23 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 94,720 | $2,106,573 | 0% | |
| 2. | 4,383 | $97,000 | 0.01% | |
| 3. | 3,308,000 | $73,570 | 2.38% | |
| 4. | 2,615,443 | $58,168 | 0.01% | |
| 5. | 2,320,406 | $51,607 | 0% |
