| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Perceptive Advisors Joseph Edelman | 4,319,496 | $383,484,855 | +15% | 5.76% |
| 2. | Paradigm Biocapital Advisors Senai Asefaw | 3,840,778 | $340,984,271 | +97% | 6.38% |
| 3. | Driehaus Capital Richard Driehaus | 2,799,166 | $248,509,957 | +1% | 1.44% |
| 4. | Tang Capital Management Kevin C. Tang | 1,892,200 | $167,989,516 | 7.63% | |
| 5. | Adage Capital Management Phill Gross And Robert Atchinson | 1,722,300 | $152,905,794 | 0.21% |