| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Vivo Capital Albert Cha And Frank Kung | 4,458,294 | $318,545,106 | -30% | 42.19% |
| 2. | Adage Capital Management Phill Gross And Robert Atchinson | 4,392,696 | $313,858,129 | +59% | 0.58% |
| 3. | VenBio Select Advisor Kurt Von Emster | 2,525,000 | $180,411,250 | 2.82% | |
| 4. | Nantahala Capital Management Wilmot B. Harkey And Daniel Mack | 1,757,023 | $125,539,293 | -56% | 4.99% |
| 5. | Citadel Investment Group Ken Griffin | 1,576,044 | $112,608,344 | +63% | 0.02% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $20.00 | 250,000 | $5,000,000.00 | 3,074,542 | 2023-09-28 | Filing | |
| $21.00 | 36,939 | $775,719.00 | 2,824,542 | 2023-09-26 | Filing | |
| $20.03 | 117,996 | $2,363,459.88 | 2,787,603 | 2023-09-26 | Filing | |
| $19.11 | 88,685 | $1,694,770.35 | 2,669,607 | 2023-09-26 | Filing | |
| $18.24 | 52,691 | $961,083.84 | 2,580,922 | 2023-09-26 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $70.11 | 3,782 | $265,156.02 | 27,036 | 2025-04-01 | Filing | |
| $71.55 | 5,937 | $424,797.10 | 6,500 | 2025-03-28 | Filing | |
| $66.95 | 23,475 | $1,571,716.98 | 28,143 | 2025-03-27 | Filing | |
| $66.00 | 50,156 | $3,310,080.33 | 51,618 | 2025-03-27 | Filing | |
| $72.64 | 91 | $6,610.16 | 61,136 | 2025-03-27 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 5,140,899 | $370,024,378 | 0.2% | |
| 2. | 2,233,473 | $159,581,640 | 0.01% | |
| 3. | 1,913,326 | $136,707,143 | 0% | |
| 4. | 1,866,326 | $133,348,993 | 0% | |
| 5. | 1,211,245 | $86,543,455 | 0.42% |
