| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Deerfield Management James E. Flynn | 1,725,640 | $67,524,293 | +24% | 1.5% |
| 2. | Marshall Wace LLP Paul Marshall And Ian Wace | 741,464 | $29,013,486 | +135% | 0.06% |
| 3. | Citadel Investment Group Ken Griffin | 563,537 | $22,051,203 | +266% | 0% |
| 4. | Parkman Healthcare Partners Greg Martinez | 239,864 | $9,385,878 | +158% | 2.04% |
| 5. | Rhenman & Partners Asset Management Henrik Rhenman | 221,255 | $8,613,457 | +13% | 0.94% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $41.30 | 2,500 | 132,179 | 2021-11-30 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $35.51 | 2,000 | 269,132 | 2023-05-11 | Filing | ||
| $35.51 | 1,000 | 271,132 | 2023-05-11 | Filing | ||
| $44.51 | 3,213 | 115,683 | 2023-05-01 | Filing | ||
| $44.51 | 2,584 | 118,896 | 2023-05-01 | Filing | ||
| $44.51 | 474 | 121,480 | 2023-05-01 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 3,641,988 | $142,510,990 | 0% | |
| 2. | 3,244,538 | $126,958,772 | 0.79% | |
| 3. | 2,966,730 | $116,088,145 | 0.02% | |
| 4. | 2,682,159 | $104,952,882 | 0% | |
| 5. | 2,461,871 | $96,333,012 | 0.04% |
