| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Farallon Capital Thomas Steyer | 14,325,692 | $527,042,209 | +6% | 2.27% |
| 2. | Baker Bros. Advisors Julian Baker And Felix Baker | 9,364,972 | $344,537,320 | +18% | 3.34% |
| 3. | Biotechnology Value Fund / BVF Inc Mark Lampert | 4,982,384 | $183,301,907 | 6.55% | |
| 4. | Holocene Advisors Brandon Haley | 3,632,952 | $133,656,304 | -2% | 0.33% |
| 5. | Deerfield Management James E. Flynn | 3,384,072 | $124,500,009 | +3% | 2.26% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $46.00 | 760,869 | $34,999,974.00 | 760,869 | 2024-12-05 | Filing | |
| $46.00 | 543,478 | $24,999,988.00 | 2,096,612 | 2024-12-05 | Filing | |
| $20.85 | 6,200 | $129,270.00 | 1,553,134 | 2023-03-10 | Filing | |
| $20.43 | 93,800 | $1,916,334.00 | 1,546,934 | 2023-03-10 | Filing | |
| $22.00 | 318,181 | $6,999,982.00 | 618,181 | 2023-03-07 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $44.26 | 1,799 | $79,623.74 | 50,425 | 2025-09-24 | Filing | |
| $45.82 | 2,160 | $98,981.78 | 88,339 | 2025-09-16 | Filing | |
| $45.82 | 5,367 | $245,942.24 | 284,047 | 2025-09-16 | Filing | |
| $45.82 | 13,411 | $614,557.73 | 452,309 | 2025-09-16 | Filing | |
| $45.82 | 4,775 | $218,813.90 | 145,900 | 2025-09-16 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 47,534 | $2,219,838 | 0% | |
| 2. | 40,006 | $1,863,079 | 0.07% | |
| 3. | 837 | $39,088 | 0% | |
| 4. | 365 | $17,046 | 0.01% | |
| 5. | 158 | $7,379 | 0% |
