| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Farallon Capital Thomas Steyer | 13,550,796 | $2,537,793,075 | -1% | 11.71% |
| 2. | Baker Bros. Advisors Julian Baker And Felix Baker | 11,443,357 | $2,143,111,899 | +20% | 10.74% |
| 3. | Darwin Global Management Abhishek Trehan | 10,629,822 | $2,047,516,314 | +381% | 54.45% |
| 4. | Paradigm Biocapital Advisors Senai Asefaw | 6,361,323 | $1,191,348,571 | -5% | 22.31% |
| 5. | Biotechnology Value Fund / BVF Inc Mark Lampert | 2,965,160 | $555,315,165 | +4% | 14.2% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $46.00 | 760,869 | $34,999,974.00 | 760,869 | 2024-12-05 | Filing | |
| $46.00 | 543,478 | $24,999,988.00 | 2,096,612 | 2024-12-05 | Filing | |
| $20.85 | 6,200 | $129,270.00 | 1,553,134 | 2023-03-10 | Filing | |
| $20.43 | 93,800 | $1,916,334.00 | 1,546,934 | 2023-03-10 | Filing | |
| $22.00 | 318,181 | $6,999,982.00 | 618,181 | 2023-03-07 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $204.72 | 301 | $61,621.44 | 52,559 | 2026-09-29 | Filing | |
| $203.91 | 1,199 | $244,484.97 | 52,860 | 2026-09-29 | Filing | |
| $202.81 | 1,000 | $202,812.70 | 54,059 | 2026-09-29 | Filing | |
| $201.72 | 1,609 | $324,573.76 | 55,059 | 2026-09-29 | Filing | |
| $200.82 | 2,200 | $441,801.36 | 56,668 | 2026-09-29 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 40,937 | $7,701,068 | 0.18% | |
| 2. | 4,848 | $995,100 | 0.01% | |
| 3. | 2,266 | $465,119 | 0.02% | |
| 4. | 354,000 | $454,472 | 0.05% | |
| 5. | 2,000 | $410,520 | 0.1% |
