| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Redmile Group Jeremy Green | 2,123,492 | $96,322 | -5% | 1.16% |
| 2. | Aquilo Capital Management Marc Schneidman | 503,444 | $22,836 | -2% | 4.74% |
| 3. | Frazier Healthcare Partners Alan Frazier | 341,954 | $15,511 | +97% | 1.19% |
| 4. | Water Street Capital Gilchrist Berg | 257,929 | $11,700 | -41% | 1.21% |
| 5. | Citadel Investment Group Ken Griffin | 213,178 | $9,670 | +209% | 0% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $22.00 | 49,000 | Large Shareholder, Other | 49,000 | 2015-09-22 | Filing | |
| $22.00 | 38,500 | Large Shareholder, Other | 38,500 | 2015-09-22 | Filing | |
| $22.00 | 87,500 | Large Shareholder, Other | 1,256,542 | 2015-09-22 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $49.08 | 4,701 | 16,372 | 2021-02-12 | Filing | ||
| $49.11 | 1,300 | 16,372 | 2021-02-08 | Filing | ||
| $45.13 | 500 | 16,372 | 2021-02-02 | Filing | ||
| $44.77 | 9,500 | 16,872 | 2021-02-02 | Filing | ||
| $44.99 | 5,211 | 280,984 | 2021-01-25 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 64,307 | $2,916,966 | 0% | |
| 2. | 26,890 | $740,013 | 0% | |
| 3. | 5,433,372 | $246,457 | 0% | |
| 4. | 3,958 | $179,527 | 0.05% | |
| 5. | 3,335,298 | $151,289 | 0% |
