Prothena Corporation plc (NASDAQ:PRTA) Q4 2025 Earnings Call Transcript
Operator: Good day, ladies and gentlemen, and welcome to the Prothena Biosciences Fourth Quarter and Full Year 2025 Financial Results Conference Call.
Prothena Corp Public Ltd Co (PRTA)
Market is closed
Sector: Healthcare
Hedge Fund Popularity
Hedge Fund Holdings
Filing Period:
Last updated on based on SEC 13F filings Last update:
| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Rubric Capital Management David Rosen | 5,000,000 | $48,950,000 | 0.45% | |
| 2. | D E Shaw D. E. Shaw | 1,611,457 | $15,776,164 | -9% | 0.01% |
| 3. | ADAR1 Capital Management Daniel Schneeberger | 1,554,535 | $15,218,898 | -2% | 0.7% |
| 4. | Palo Alto Investors William Leland Edwards | 1,143,155 | $11,191,487 | -6% | 1.55% |
| 5. | Renaissance Technologies Jim Simons | 697,615 | $6,829,651 | +15% | 0.01% |
Insider Trading: Purchases See All
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $8.79 | 50,000 | $439,430.00 | 800,000 | 2026-08-20 | Filing | |
| $8.62 | 3,500 | $30,167.20 | 83,500 | 2026-08-07 | Filing | |
| $8.62 | 34,000 | $293,052.80 | 790,000 | 2026-08-07 | Filing | |
| $7.90 | 20,000 | $157,990.00 | 756,000 | 2026-06-16 | Filing | |
| $8.17 | 125,000 | $1,021,225.00 | 1,061,000 | 2026-06-11 | Filing |
Insider Trading: Sales See All
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $8.47 | 7,662 | $64,919.36 | 55,782 | 2026-07-29 | Filing | |
| $8.47 | 8,386 | $71,055.42 | 35,745 | 2026-07-29 | Filing | |
| $7.64 | 1,984,053 | $15,164,712.29 | 5,304,596 | 2025-05-06 | Filing | |
| $8.11 | 977,693 | $7,930,165.69 | 7,288,649 | 2025-05-05 | Filing | |
| $8.36 | 3,317,938 | $27,744,929.35 | 8,266,342 | 2025-05-02 | Filing |
Institutional Investors' Holdings
Filing Period:
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 7,199,218 | $70,480,344 | 0% | |
| 2. | 4,867,955 | $47,657,280 | 0% | |
| 3. | 2,393,424 | $23,431,621 | 0% | |
| 4. | 1,651,293 | $16,166,158 | 0% | |
| 5. | 1,125,877 | $11,024,980 | 0% |
News See All
Prothena Corporation plc (PRTA): A Bull Case Theory
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Piper Sandler Reduces Prothena (PRTA) Price Target to $81 from $110 Following AFFIRM-AL Trial Discontinuation
The price target decrease followed the company's May 23 announcement stating that its Phase 3 AFFIRM-AL clinical trial for Birtamimab in AL Amyloidosis patients failed to meet the primary endpoint, resulting...
Chardan Lowers Prothena (PRTA) Price Target Following AFFIRM-AL Trial Failure
Although the firm is bullish on Prothena Corporation plc (NASDAQ:PRTA), it reduced its price target after the company announced the discontinuation of its Phase 3 AFFIRM-AL clinical trial for Birtamimab...
H.C. Wainwright Maintains Buy Rating on Prothena Corporation (NASDAQ:PRTA), Cuts PT
The price target decrease followed the company's announcement on May 23 that its Phase 3 AFFIRM-AL clinical trial for Birtamimab in AL Amyloidosis patients had failed to meet the primary endpoint.
Citizens JMP Slashes Prothena (PRTA) to $29 from $78 After AFFIRM-AL Trial Fails
The notable price target decrease came after Prothena Corporation plc (NASDAQ:PRTA) announced negative results from the Phase 3 AFFIRM-AL trial for birtamimab in AL amyloidosis on May 23.
Oppenheimer Downgrades Prothena Corporation (NASDAQ:PRTA) to Perform from Outperform
This rating update came after Prothena Corporation's (NASDAQ:PRTA) May 23 announcement that its Phase 3 AFFIRM-AL trial for birtamimab in amyloid light chain amyloidosis failed to meet the primary endpoint...
Jefferies Downgrades Prothena Corporation (PRTA) After Negative Trial Results
The considerable price target reduction followed the company's announcement regarding the discontinuation of its Phase 3 AFFIRM-AL clinical trial for Birtamimab in AL Amyloidosis patients, as it could...
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