| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Suvretta Capital Management Aaron Cowen | 1,153,496 | $143,783,276 | +30% | 3.67% |
| 2. | Biotechnology Value Fund / BVF Inc Mark Lampert | 960,989 | $119,787,279 | +10% | 3.82% |
| 3. | Woodline Partners Michael Rockefeller And Karl Kroeker | 317,517 | $39,578,494 | +6% | 0.15% |
| 4. | Siren L.L.C. Raymond Debbane | 257,485 | $32,095,505 | +244% | 0.89% |
| 5. | BioImpact Capital Mpm Capital | 206,404 | $25,728,259 | +1% | 1.99% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $112.30 | 445 | $49,973.50 | 187,616 | 2026-03-30 | Filing | |
| $125.00 | 4,000 | $500,000.00 | 187,171 | 2026-02-27 | Filing | |
| $125.00 | 2,400 | $300,000.00 | 47,812 | 2026-02-27 | Filing | |
| $20.27 | 2,490 | $50,472.30 | 13,516 | 2025-04-09 | Filing | |
| $20.13 | 2,500 | $50,325.00 | 183,171 | 2025-04-09 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $112.23 | 25 | $2,805.75 | 0 | 2026-06-17 | Filing | |
| $111.31 | 1,887 | $210,047.25 | 25 | 2026-06-17 | Filing | |
| $110.26 | 2,390 | $263,519.97 | 1,912 | 2026-06-17 | Filing | |
| $111.90 | 48 | $5,370.96 | 0 | 2026-05-20 | Filing | |
| $111.30 | 891 | $99,165.00 | 48 | 2026-05-20 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 52 | $7,947 | 0% | |
| 2. | 37 | $5,654 | 0% | |
| 3. | 11 | $1,681 | 0% |
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